Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4460701 | 0.99 | FYN (0.40) | FYNALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2678759 | 0.98 | FYN (0.42) | FYNALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL2678564 | 0.97 | FYN (0.41) | FYNALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2678945 | 0.95 | FYN (0.43) | FYNALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2679330 | 0.88 | HSD11B1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL2678054 | 0.85 | HSD11B1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL4469713 | 0.85 | RXFP1 (0.41) | FYNSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL4480044 | 0.84 | RXFP1 (0.40) | FYNSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2678305 | 0.83 | KDM1A (0.47) | FYNALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL2678397 | 0.82 | RXFP1 (0.43) | FYNSMN1; SMN2NOS1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |