Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521742 | 0.75 | CA12 (0.40) | CA12CA1CA2TYRCA7 | |
| SCHEMBL29536245 | 0.63 | HCAR2 (0.52) | CA12CA1CA2TYRCA7 | |
| SCHEMBL15150027 | 0.61 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL403042 | 0.61 | CA12 (0.70) | CA12CA1CA2TYRCA7 | |
| SCHEMBL403043 | 0.61 | CA12 (0.70) | CA12CA1CA2TYRCA7 | |
| SCHEMBL5259514 | 0.61 | CA12 (0.70) | CA12CA1CA2TYRCA7 | |
| SCHEMBL6821064 | 0.61 | AKR1C3 (0.56) | CA12CA1CA2TYRCA7 | |
| SCHEMBL6821063 | 0.61 | AKR1C3 (0.56) | CA12CA1CA2TYRCA7 | |
| SCHEMBL71224 | 0.61 | CA12 (0.84) | CA12CA1CA2TYRCA7 | |
| SCHEMBL5057418 | 0.61 | CA12 (0.84) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417082-B1 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | UNIV TEXAS (US) | 2016-03-16 | — | — | EP | disclosed |
| US-8901365-B2 | Catalytic Wittig and Mitsunobu reactions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2417082-A2 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120029211-A1 | Catalytic Wittig and Mitsunobu Reactions | THE UNIVERSITY OF TEXAS AT ARLINGTON | 2012-02-02 | — | — | US | disclosed |
| WO-2010118042-A2 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | BOARD OF REGENTS THE UNIVERSITY OF TEXAS AT ARLINGTON (US) | 2010-10-14 | — | — | WO | disclosed |