Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821064 | 1.00 | AKR1C3 (0.56) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL28928255 | 0.91 | CA12 (0.59) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL17705228 | 0.90 | AKR1C3 (0.57) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL2334343 | 0.88 | AKR1C3 (0.50) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL21835129 | 0.88 | BACE1 (0.54) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL23380718 | 0.88 | AKR1C3 (0.50) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL16307036 | 0.88 | BACE1 (0.54) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL2334339 | 0.88 | AKR1C3 (0.50) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL29937522 | 0.88 | BACE1 (0.54) | AKR1C3CA1CA2CA12TYR | |
| SCHEMBL322249 | 0.82 | HSD17B3 (0.67) | CA1CA2CA12TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103525434-B | Polymerizable compound and its purposes for liquid crystal display | 默克专利股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| CN-103525434-A | Polymerizable compounds and use thereof in liquid crystal displays | MERCK PATENT GMBH | 2014-01-22 | — | — | CN | disclosed |
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |