Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279994 | 0.84 | CYP1A2 (0.47) | CYP1A2CYP3A4MAPTGAACREBBP | |
| SCHEMBL510531 | 0.76 | KDM4E (0.49) | CYP3A4MAPTGAAKMT2AHPGD | |
| SCHEMBL399174 | 0.76 | ATM (0.49) | MAPTGAANPSR1KMT2AHPGD | |
| SCHEMBL3033303 | 0.76 | ALDH1A1 (0.40) | CYP1A2CYP3A4MAPTGAAESR1 | |
| SCHEMBL1411774 | 0.75 | CYP1A2 (0.76) | CYP1A2CYP3A4MAPTCREBBPBRD4 | |
| SCHEMBL3399851 | 0.73 | KDM4E (0.44) | CYP3A4MAPTGAANPSR1KMT2A | |
| SCHEMBL401727 | 0.73 | ATM (0.44) | MAPTGAANPSR1KMT2AHPGD | |
| SCHEMBL10815675 | 0.71 | KDM4E (0.56) | CYP1A2CYP3A4MAPTGAACREBBP | |
| SCHEMBL2150911 | 0.71 | CYP1A2 (0.57) | CYP1A2CYP3A4MAPTCREBBPBRD4 | |
| SCHEMBL11018436 | 0.70 | KDM4E (0.46) | CYP1A2CYP3A4MAPTGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |