Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302890 | 0.90 | KDM4E (0.43) | ALDH1A1KDM4EKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3495823 | 0.89 | MCHR1 (0.36) | ALDH1A1KDM4EKMT2ASMN1; SMN2TP53 | |
| SCHEMBL14303283 | 0.88 | KDM4E (0.36) | ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL3495444 | 0.85 | TP53 (0.41) | ALDH1A1KDM4EKMT2ASMN1; SMN2LMNA | |
| SCHEMBL4965499 | 0.85 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL14395082 | 0.85 | MDM4 (0.34) | ALDH1A1KDM4EKMT2ASMN1; SMN2TSHR | |
| SCHEMBL14302885 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2ASMN1; SMN2TP53 | |
| SCHEMBL4962801 | 0.84 | KDM4E (0.34) | ALDH1A1KDM4EKMT2ASMN1; SMN2CNR2 | |
| SCHEMBL3495927 | 0.84 | POLB (0.42) | KDM4EKMT2ALMNAHPGDTP53 | |
| SCHEMBL4964868 | 0.83 | CYP19A1 (0.39) | ALDH1A1KDM4EKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751157-B1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER (US) | 2007-10-03 | — | — | EP | claimed |