Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | F10 | P00742 | 2/20 | 0.61 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123360 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2295551 | 0.80 | NPC1 (0.71) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7251634 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL38660966 | 0.79 | MEN1 (0.60) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11557673 | 0.79 | KDM4E (0.60) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL31550547 | 0.79 | HDAC8 (0.60) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL6404086 | 0.79 | HDAC8 (0.60) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL3821744 | 0.78 | F10 (0.93) | ALDH1A1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28249518 | 0.78 | POLB (0.67) | ALDH1A1KDM4ECYP1A2CYP2C19NPC1 | |
| SCHEMBL6450099 | 0.78 | MAOB (0.65) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |