Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31550547 | 1.00 | HDAC8 (0.60) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7900610 | 0.93 | RAB9A (0.58) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7907533 | 0.92 | MAOB (0.62) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1647498 | 0.90 | FOLH1 (0.63) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1448026 | 0.90 | MAOB (0.61) | KDM4ERAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL6450099 | 0.90 | MAOB (0.65) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4756552 | 0.89 | MAOB (0.63) | KDM4ESMN1; SMN2MCL1MAOBCTSV | |
| SCHEMBL11283190 | 0.88 | MAOB (0.59) | KDM4ERAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL11557673 | 0.88 | KDM4E (0.60) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5228333 | 0.88 | HDAC8 (0.57) | HDAC8KDM4ERAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710462-B1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LTD (NZ) | 2026-05-13 | — | — | EP | disclosed |
| US-20240309036-A1 | Phenol Compound-Linked Pentagalloyl Glucose Derivatives and Uses Thereof | GENTRIBIO INC. (KR) | 2024-09-19 | — | — | US | disclosed |
| CN-111184866-B | Combination treatment of bacterial infections | 香港中文大学 | 2023-12-19 | — | — | CN | disclosed |
| WO-2023214629-A1 | PHENOL COMPOUND-LINKED PENTAGALLOYL GLUCOSE DERIVATIVE AND USE THEREOF | 주식회사 젠트리바이오 | 2023-11-09 | — | — | WO | disclosed |
| US-20230139366-A1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2023-05-04 | — | — | US | disclosed |
| US-20230139366-A1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2023-05-04 | — | — | US | disclosed |
| US-20230139366-A1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2023-05-04 | — | — | US | disclosed |
| US-11510980-B2 | Brartemicin analogues | VICTORIA LINK LTD. (NZ) | 2022-11-29 | — | — | US | disclosed |
| US-20210177965-A1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2021-06-17 | — | — | US | disclosed |
| US-20210177965-A1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2021-06-17 | — | — | US | disclosed |
| EP-3710462-A1 | BRARTEMICIN ANALOGUES | Victoria Link Limited (NZ) | 2020-09-23 | — | — | EP | disclosed |
| CN-111184866-A | Combination therapy for bacterial infections | 香港中文大学 | 2020-05-22 | — | — | CN | disclosed |
| WO-2015161830-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-29 | — | — | WO | disclosed |
| US-6949585-B2 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | EISAI CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040082805-A1 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1375465-A9 | CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1375479-A1 | PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139366-A1 | BRARTEMICIN ANALOGUES | RXFP1, RXFP2, RXFP4 | HDAC8 2334/4885KDM4E 3694/4885RAB9A 1030/4885 |
| US-20040082805-A1 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | CCR1, CCL2, CCR5 | HDAC8 2718/4885KDM4E 2070/4885RAB9A 4319/4885 |
| US-20240309036-A1 | Phenol Compound-Linked Pentagalloyl Glucose Derivatives and Uses Thereof | UGGT1, GCK, GCG | HDAC8 675/4885KDM4E 968/4885RAB9A 2393/4885 |
| US-20210177965-A1 | BRARTEMICIN ANALOGUES | RXFP1, RXFP2, CMKLR1 | HDAC8 2472/4885KDM4E 3994/4885RAB9A 975/4885 |
| US-11510980-B2 | Brartemicin analogues | RXFP1, RXFP2, CMKLR1 | HDAC8 2472/4885KDM4E 3994/4885RAB9A 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.