Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795605 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL5226969 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL10491905 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL10491840 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL9787888 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL10617486 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL10619632 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL15201350 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL15201476 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB | |
| SCHEMBL10616783 | 1.00 | ALDH1A1 (0.35) | ALDH1A1EBPSIGMAR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | claimed |
| EP-0296199-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA, Vithal J. (US) | 1988-12-28 | — | — | EP | claimed |
| WO-1988004938-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA VITHAL J (US) | 1988-07-14 | — | — | WO | claimed |
| CN-109311929-B | SECO macrolide compounds | 塞尔维塔公司 | 2022-10-04 | — | — | CN | disclosed |
| EP-1298123-B1 | PURIFIED POLYOXYPROPYLENE FATTY ACID ISOPROPANOLAMIDE SURFACTANTS, PRODUCTION THEREOF AND DETERGENT COMPOSITIONS CONTAINING THE SURFACTANTS | KAWAKEN FINE CHEMICALS CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-7067471-B2 | Process for producing a refined product of polyoxyproylene fatty acid isopropanolamide surfactant | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20050187135-A1 | Process for producing a refined product of polyoxyproylene fatty acid isopropanolamide surfactant | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
| US-20030176311-A1 | Purified polyoxypropylene fatty acid isopropanolamide surfactants, production thereof and detergent compositions containing the surfactants | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1298123-A1 | PURIFIED POLYOXYPROPYLENE FATTY ACID ISOPROPANOLAMIDE SURFACTANTS, PRODUCTION THEREOF AND DETERGENT COMPOSITIONS CONTAINING THE SURFACTANTS | Kawaken Fine Chemicals Co., Ltd. (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5030629-A | Transdermal Administration Of Cardiovascular Agents | THERAPEUTIC PATCH RESEARCH N.V. | 1991-07-09 | — | — | US | disclosed |
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | disclosed |