⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361966 | 1.00 | — | — | |
| SCHEMBL11122946 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL201249 | 0.98 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL201248 | 0.98 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL7350919 | 0.98 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL6392619 | 0.96 | KMT2A (0.40) | — | |
| Hydrochloric Acid SCHEMBL6395633 | 0.96 | KMT2A (0.40) | — | |
| SCHEMBL28052844 | 0.83 | — | — | |
| SCHEMBL4571091 | 0.82 | KMT2A (0.41) | — | |
| SCHEMBL5493487 | 0.82 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20230348493-A1 | COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| CN-104447947-A | Process for producing pidotimod | CHENGDU YILUKANG MEDICAL TECHNOLOGY & SERVICE CO L | 2015-03-25 | — | — | CN | disclosed |
| EP-1406872-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2007-12-19 | — | — | EP | disclosed |
| US-7098239-B2 | Dipeptidyl peptidase inhibitors for the treatment of diabetes | MERCK & CO., INC (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1406872-A4 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040176428-A1 | Dipeptidyl peptidase inhibitors for the treatment of diabetes | MERCK SHARP & DOHME CORP. | 2004-09-09 | — | — | US | disclosed |
| EP-1406872-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | Merck & Co., Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003000180-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO., INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| CN-1017435-B | PROCESS FOR PREPARATION OF GLYCEROL DERIVATIVES | NIPPON CHEMIPHAR CO (JP) | 1992-07-15 | — | — | CN | disclosed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| CN-1030239-A | The preparation method of new glycerol derivative | NIPPON CHEMIPHAR CO (JP) | 1989-01-11 | — | — | CN | disclosed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |