Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675696 | 1.00 | KMT2A (0.41) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5493487 | 1.00 | KMT2A (0.41) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL2675695 | 0.98 | KMT2A (0.40) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL5362921 | 0.98 | KMT2A (0.40) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5224314 | 0.82 | — | — | |
| SCHEMBL3361966 | 0.82 | — | — | |
| SCHEMBL11122946 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL201248 | 0.80 | KMT2A (0.41) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL201249 | 0.80 | KMT2A (0.41) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7350919 | 0.80 | KMT2A (0.41) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084044-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| EP-4462999-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-118541030-A | Protoporphyrinogen oxidase inhibitors | 恩科化学公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023137307-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| EP-2130825-B1 | N-SUBSTITUTED THIOMORPHOLINE DERIVATIVES AS THE INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND THE PHARMACEUTICAL USES THEREOF | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO LTD (CN) | 2014-08-06 | — | — | EP | disclosed |
| US-8173643-B2 | N-substituted thiomorpholine derivatives as the inhibitors of dipeptidyl peptidase IV and the pharmaceutical uses thereof | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2012-05-08 | — | — | US | disclosed |
| US-8173643-B2 | N-substituted thiomorpholine derivatives as the inhibitors of dipeptidyl peptidase IV and the pharmaceutical uses thereof | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2012-05-08 | — | — | US | disclosed |
| US-20100113433-A1 | N-Substituted Thiomorpholine Derivatives as the Inhibitors of Dipeptidyl Peptidase IV and the Pharmaceutical Uses Thereof | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113433-A1 | N-Substituted Thiomorpholine Derivatives as the Inhibitors of Dipeptidyl Peptidase IV and the Pharmaceutical Uses Thereof | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2010-05-06 | — | — | US | disclosed |
| EP-2130825-A1 | N-SUBSTITUTED THIOMORPHOLINE DERIVATIVES AS THE INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND THE PHARMACEUTICAL USES THEREOF | Beijing Molecule Science and Technology Co., Ltd. (CN) | 2009-12-09 | — | — | EP | disclosed |
| US-7304057-B2 | Substituted 6-membered N-heterocyclic compounds and method for their use as neurological regulator | Institute of Pharmacology and Toxicology Accademy of Military Medical Sciences P.L.A. China (CN) | 2007-12-04 | — | — | US | disclosed |
| US-7304057-B2 | Substituted 6-membered N-heterocyclic compounds and method for their use as neurological regulator | Institute of Pharmacology and Toxicology Accademy of Military Medical Sciences P.L.A. China (CN) | 2007-12-04 | — | — | US | disclosed |
| US-7304057-B2 | Substituted 6-membered N-heterocyclic compounds and method for their use as neurological regulator | Institute of Pharmacology and Toxicology Accademy of Military Medical Sciences P.L.A. China (CN) | 2007-12-04 | — | — | US | disclosed |
| US-20050130958-A1 | Substituted 6−membered n−heterocyclic compounds and their uses as neurological regulator | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084044-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, CYP4X1, PNPO | KMT2A 4160/4885CHRNB2 4802/4885CHRNA4 4759/4885 |
| US-20100113433-A1 | N-Substituted Thiomorpholine Derivatives as the Inhibitors of Dipeptidyl Peptidase IV and the Pharmaceutical Uses Thereof | DPP4, DPP3, DPP7 | KMT2A 4115/4885CHRNB2 2893/4885CHRNA4 1554/4885 |
| US-20050130958-A1 | Substituted 6−membered n−heterocyclic compounds and their uses as neurological regulator | BDNF, NGF, NTRK2 | KMT2A 3699/4885CHRNB2 299/4885CHRNA4 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.