SCHEMBL5224468

SCHEMBL5224468

Cc1nc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)CC2)sc1OC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCC2 Q92887 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3280848 0.86 ABCC2 (0.55) ABCC2
SCHEMBL15122087 0.85 ABCC2 (0.53) ABCC2
SCHEMBL15122156 0.85 ABCC2 (0.68) ABCC2
SCHEMBL5225687 0.83 ABCC2 (0.57) ABCC2
SCHEMBL5223006 0.83 ABCC2 (0.46) ABCC2
SCHEMBL3287171 0.82 ABCC2 (0.50) ABCC2
SCHEMBL3285115 0.79 MAPT (0.51) ABCC2
SCHEMBL3281310 0.79 ABCC2 (0.57) ABCC2
SCHEMBL3282156 0.79 ABCC2 (0.53) ABCC2
SCHEMBL3288440 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1664025-B1 PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY ASTRAZENECA AB (SE) 2007-09-19 EP claimed