Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.57 |
| ▸ | PPARA | Q07869 | 17/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224733 | 0.92 | PPARA (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5228134 | 0.92 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5225327 | 0.85 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5261705 | 0.84 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5441436 | 0.83 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5228532 | 0.82 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5225422 | 0.79 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL5231246 | 0.78 | FFAR1 (0.60) | PPARGPPARA | |
| SCHEMBL5422265 | 0.78 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL5227055 | 0.78 | PPARG (0.58) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | claimed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | claimed |
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |