Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.56 |
| ▸ | PPARG | P37231 | 13/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225331 | 0.92 | PPARG (0.57) | PPARAPPARGPPARD | |
| SCHEMBL5231246 | 0.86 | FFAR1 (0.60) | PPARAPPARGFFAR1MAPT | |
| SCHEMBL5224731 | 0.85 | PPARA (0.58) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5228134 | 0.84 | PPARG (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5231167 | 0.84 | PPARG (0.55) | PPARAPPARGFFAR1MAPT | |
| SCHEMBL5428415 | 0.83 | PPARA (0.58) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL5229138 | 0.82 | PPARA (0.48) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL5231601 | 0.79 | PPARA (0.55) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5225327 | 0.77 | PPARG (0.59) | PPARAPPARGPPARD | |
| SCHEMBL5226386 | 0.77 | PPARA (0.53) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |