Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.60 |
| ▸ | FABP1 | P07148 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282205 | 0.93 | MAPK14 (0.59) | MAPK14FABP1 | |
| SCHEMBL5227756 | 0.90 | MAPK14 (0.54) | MAPK14FABP1MAPK11 | |
| SCHEMBL5227603 | 0.87 | MAPK14 (0.53) | MAPK14FABP1MAPK11 | |
| SCHEMBL5229767 | 0.85 | MAPK14 (0.61) | MAPK14MAPK11 | |
| SCHEMBL5229479 | 0.84 | MAPK14 (0.67) | MAPK14MAPK11 | |
| SCHEMBL5228095 | 0.83 | MAPK14 (0.59) | MAPK14MAPK11 | |
| SCHEMBL5228702 | 0.80 | MAPK14 (0.49) | MAPK14MAPK11 | |
| SCHEMBL5225990 | 0.80 | MAPK14 (0.45) | MAPK14FABP1 | |
| SCHEMBL5226833 | 0.79 | MAPK14 (0.42) | MAPK14FABP1 | |
| SCHEMBL5228281 | 0.79 | MAPK14 (0.51) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1842851-A2 | Novel compounds | Smithkline Beecham Corporation (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1265900-B1 | 1,5-DISUBSTITUTED-3,4-DIHYDRO-1H-PYRIMIDO 4,5-D|PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CSBP/P38 KINASE MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 2007-05-16 | — | — | EP | disclosed |