SCHEMBL5225527

SCHEMBL5225527

CC(=O)NCC1CN(c2cc(F)c(-c3ccc(-c4cc(CO)on4)c(F)c3)c(F)c2)C(=O)O1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.60
CALML3 P27482 5/20 0.50
MAOB P27338 3/20 0.50
PTGS1 P23219 2/20 0.50
SDHA P31040 2/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2897905 1.00 MAOA (0.60) MAOACALML3MAOBPTGS1SDHA
SCHEMBL5221897 0.93 MAOA (0.65) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2889916 0.93 MAOA (0.65) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2899489 0.84 MAOA (0.62) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2890751 0.82 MAOA (0.57) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2896814 0.82 MAOA (0.59) MAOACALML3MAOBPTGS1SDHA
SCHEMBL16562024 0.81 MAOA (0.59) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2900127 0.81 MAOA (0.55) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2898315 0.81 MAOA (0.57) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2899376 0.81 MAOA (0.48) MAOACALML3MAOBPTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed