Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253234 | 1.00 | HMGCR (0.83) | HMGCR | |
| SCHEMBL6418791 | 0.93 | HMGCR (0.87) | HMGCR | |
| SCHEMBL5991667 | 0.93 | HMGCR (0.87) | HMGCR | |
| SCHEMBL5223141 | 0.92 | HMGCR (0.73) | HMGCR | |
| SCHEMBL5223752 | 0.91 | HMGCR (0.88) | HMGCR | |
| SCHEMBL4730997 | 0.91 | HMGCR (1.00) | HMGCR | |
| SCHEMBL1600617 | 0.91 | HMGCR (1.00) | HMGCR | |
| SCHEMBL6362278 | 0.91 | HMGCR (0.78) | HMGCR | |
| SCHEMBL5329246 | 0.90 | HMGCR (0.98) | HMGCR | |
| SCHEMBL5992425 | 0.90 | HMGCR (0.79) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740549-A2 | NOVEL IMIDAZOLES | Warner-Lambert Company LLC (US) | 2007-01-10 | — | — | EP | claimed |
| WO-2005105079-A2 | NOVEL IMIDAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| EP-1740549-A2 | NOVEL IMIDAZOLES | Warner-Lambert Company LLC (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105079-A2 | NOVEL IMIDAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |