Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 17/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910609 | 1.00 | CTSK (0.49) | CTSKBTKDPP4DPP8DPP9 | |
| SCHEMBL29933492 | 0.77 | CTSK (0.53) | CTSKDPP4DPP8DPP9 | |
| SCHEMBL3597277 | 0.76 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL2896482 | 0.75 | DPP4 (0.56) | CTSKDPP4DPP8DPP9 | |
| SCHEMBL240005 | 0.75 | DPP4 (0.56) | CTSKDPP4DPP8DPP9 | |
| SCHEMBL1357066 | 0.75 | DPP4 (0.56) | CTSKDPP4DPP8DPP9 | |
| SCHEMBL10106774 | 0.74 | DPP4 (0.66) | DPP4DPP8DPP9 | |
| SCHEMBL2743710 | 0.74 | DPP4 (0.66) | DPP4DPP8DPP9 | |
| SCHEMBL8268495 | 0.74 | DPP4 (0.78) | DPP4DPP8DPP9 | |
| SCHEMBL25455746 | 0.74 | BTK (0.54) | CTSKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799639-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | Glenmark Pharmaceuticals S.A. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006040625-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-04-20 | — | — | WO | disclosed |