Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.40 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.39 |
| ▸ | APEX1 | P27695 | 7/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225714 | 1.00 | AKR1C3 (0.55) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL14086414 | 0.86 | AKR1C3 (0.52) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL15709486 | 0.82 | AKR1C3 (0.47) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL10634979 | 0.82 | APP (0.51) | AKR1C3APEX1TUBB4ATUBBTUBA3C | |
| SCHEMBL15709484 | 0.82 | AKR1C3 (0.47) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL10634987 | 0.82 | APP (0.51) | AKR1C3APEX1TUBB4ATUBBTUBA3C | |
| SCHEMBL2462983 | 0.80 | AKR1C3 (0.82) | AKR1C3TBXAS1APEX1KDM4EGLA | |
| SCHEMBL2462984 | 0.80 | AKR1C3 (0.82) | AKR1C3TBXAS1APEX1KDM4EGLA | |
| SCHEMBL8746638 | 0.79 | AKR1C3 (0.61) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL3033605 | 0.79 | AKR1C3 (0.67) | AKR1C3TBXAS1APEX1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758857-A1 | INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006029912-A1 | INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-03-23 | — | — | WO | disclosed |