SCHEMBL2462984

SCHEMBL2462984

CC(=Cc1ccc(C=C(C)C(=O)O)cc1)C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.82
TBXAS1 P24557 5/20 0.51
HTT P42858 1/20 0.48
ALDH1A1 P00352 2/20 0.48
GLA P06280 1/20 0.48
POLB P06746 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 1/20 0.46
TP53 P04637 1/20 0.45
APEX1 P27695 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2462983 1.00 AKR1C3 (0.82) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL2732933 0.93 AKR1C3 (0.72) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL3414243 0.93 AKR1C3 (0.72) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL126545 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL83882 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1KDM4E
SCHEMBL9956060 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL126544 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL2406192 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1GLA
SCHEMBL83883 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1KDM4E
SCHEMBL474138 0.91 AKR1C3 (0.69) AKR1C3TBXAS1HTTALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
WO-2002031026-A2 HIGH REFRACTIVE INDEX WAVEGUIDE POLYMERS CORNING INCORPORATED (US) 2002-04-18 WO claimed
EP-0644232-B1 Free radical cured rubber GOODYEAR TIRE & RUBBER (US) 1997-03-05 EP claimed
US-12251372-B2 Antileishmanial compounds, compositions and use thereof TRUSTEES OF BOSTON UNIVERSITY 2025-03-18 US disclosed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US disclosed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO disclosed
EP-1632281-B1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM & HAAS (US) 2011-09-14 EP disclosed
EP-1510318-B1 Process for manufacturing polymers ROHM & HAAS (US) 2009-07-01 EP disclosed
EP-1092421-B1 Method for preparing ultraviolet radiation absorbing compositions ROHM & HAAS (US) 2007-03-21 EP disclosed
EP-1632281-A1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM AND HAAS COMPANY (US) 2006-03-08 EP disclosed
US-20050203215-A1 Polymer carriers and process UGAZIO STEPHEN P J (FR) 2005-09-15 US disclosed
US-20050043453-A1 Process for manufacturing polymers CHANG CHING-JEN (US) 2005-02-24 US disclosed
US-6719932-B2 EMULSION POLYMERIZING MONOMERS TO FORM A DISCRETE CROSSLINKED SHELL ENCASING A CORE WITH A POLYDISPERSITY OF 1.3-1 SHIPLEY COMPANY, L.L.C. 2004-04-13 US disclosed
US-20030031864-A1 Particles and a process for preparing the same ROHM AND HAAS COMPANY 2003-02-13 US disclosed
EP-0915147-B1 Process for preparing particles ROHM & HAAS (US) 2003-01-02 EP disclosed
US-20020197469-A1 PARTICLES AND A PROCESS FOR PREPARING THE SAME CLIKEMAN RICHARD ROY (US) 2002-12-26 US disclosed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US disclosed
WO-2002031026-A2 HIGH REFRACTIVE INDEX WAVEGUIDE POLYMERS CORNING INCORPORATED (US) 2002-04-18 WO disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed
EP-0915147-A2 Particles and a process for preparing the same ROHM AND HAAS COMPANY (US) 1999-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF MPO, SSB, SGMS2 AKR1C3 3054/4885TBXAS1 1186/4885HTT 3606/4885
US-12251372-B2 Antileishmanial compounds, compositions and use thereof MPO, SSB, SGMS2 AKR1C3 3054/4885TBXAS1 1186/4885HTT 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.