SCHEMBL5225893

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13415301	0.80	L3MBTL1 (0.69)	MAOAMAOBCA12CA1CA2
	SCHEMBL8436680	0.80	MAPT (0.61)	S1PR1MAOAMAOBCA12CA1
	SCHEMBL5226319	0.79	NPC1 (0.46)	S1PR1MAOAMAOBCA12CA1
	SCHEMBL15307622	0.78	L3MBTL1 (0.58)	HRH3MAOAMAOBCA12CA1
	SCHEMBL4118890	0.78	L3MBTL1 (0.53)	MAOAMAOBCA12CA1CA2
	SCHEMBL704133	0.78	L3MBTL1 (0.53)	MAOAMAOBCA12CA1CA2
	SCHEMBL856937	0.78	PLK1 (0.55)	S1PR1MAOAMAOBCA12CA1
	SCHEMBL5568124	0.78	PLK1 (0.52)	MAOAMAOBCA12CA1CA2
	SCHEMBL5222513	0.78	HRH3 (0.45)	HRH3S1PR1MAOAMAOBCA12
	SCHEMBL5224075	0.78	NPC1 (0.43)	S1PR1MAOAMAOBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.