SCHEMBL5225979

SCHEMBL5225979

CC(C)N(CCN1CCCCC1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2CC(N)=O)C1=O

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5227596 0.93 F10 (0.73) F10
SCHEMBL5225791 0.85 F10 (0.61) F10
SCHEMBL5222660 0.84 F10 (1.00) F10
SCHEMBL5225712 0.84 F10 (1.00) F10
Formic Acid SCHEMBL5228248 0.81 F10 (0.94) F10
SCHEMBL5224453 0.77 F10 (1.00) F10
SCHEMBL6608213 0.76 F10 (0.83) F10
Formic Acid SCHEMBL5224437 0.75 F10 (0.79) F10
SCHEMBL5225582 0.75 F10 (0.85) F10
SCHEMBL5222636 0.75 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-B1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2007-09-12 EP claimed