Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 18/20 | 0.51 |
| ▸ | PPARA | Q07869 | 18/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257668 | 0.96 | KDR (0.51) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5223343 | 0.94 | PPARA (0.56) | PPARGPPARA | |
| SCHEMBL5264572 | 0.90 | PPARA (0.42) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5228875 | 0.89 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL5226635 | 0.88 | PPARG (0.57) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5263579 | 0.88 | TP53 (0.53) | PPARGPPARACYP2C9KCNH2TP53 | |
| SCHEMBL5263779 | 0.88 | FFAR1 (0.51) | PPARGPPARATP53MAPT | |
| SCHEMBL5228999 | 0.86 | PPARA (0.50) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5432230 | 0.85 | PPARG (0.51) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5228228 | 0.84 | TP53 (0.47) | PPARGPPARACYP2C9KCNH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |