Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.42 |
| ▸ | PPARG | P37231 | 15/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227814 | 0.94 | PPARA (0.46) | PPARAPPARGKDM4EPPARD | |
| SCHEMBL5229138 | 0.93 | PPARA (0.48) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL5226643 | 0.90 | KDR (0.52) | PPARAPPARGKDRCYP2C9KCNH2 | |
| SCHEMBL5229976 | 0.88 | PPARA (0.47) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL5228532 | 0.87 | PPARG (0.50) | PPARAPPARGKDM4EPPARD | |
| SCHEMBL5257668 | 0.86 | KDR (0.51) | PPARAPPARGKDRCYP2C9KCNH2 | |
| SCHEMBL5226465 | 0.86 | PPARA (0.44) | PPARAPPARGKDRKDM4EKMT2A | |
| SCHEMBL5223343 | 0.84 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL14361125 | 0.84 | PPARA (0.46) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL5228875 | 0.83 | PPARA (0.51) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | claimed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | claimed |