Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.42 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227416 | 1.00 | TACR1 (0.42) | TACR1PRKG1SLC9A3TP53MAPT | |
| Hydrochloric Acid SCHEMBL4131113 | 0.99 | TACR1 (0.42) | TACR1PRKG1SLC9A3TP53MAPT | |
| Hydrochloric Acid SCHEMBL4131116 | 0.99 | TACR1 (0.42) | TACR1PRKG1SLC9A3TP53MAPT | |
| SCHEMBL5198139 | 0.93 | TACR1 (0.37) | TACR1PRKG1TAAR1 | |
| SCHEMBL5198136 | 0.93 | TACR1 (0.37) | TACR1PRKG1TAAR1 | |
| Hydrochloric Acid SCHEMBL4126780 | 0.92 | TACR1 (0.36) | TACR1PRKG1TAAR1 | |
| Hydrochloric Acid SCHEMBL4126783 | 0.92 | TACR1 (0.36) | TACR1PRKG1TAAR1 | |
| SCHEMBL5198694 | 0.89 | TACR1 (0.42) | TACR1SLC9A3TAAR1SIGMAR1 | |
| SCHEMBL4137188 | 0.89 | TACR1 (0.42) | TACR1SLC9A3TAAR1SIGMAR1 | |
| SCHEMBL4126854 | 0.89 | TACR1 (0.42) | TACR1SLC9A3TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1710240-B1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | SERVIER LAB (FR) | 2007-12-05 | — | — | EP | disclosed |
| EP-1710240-A1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | Les Laboratoires Servier (FR) | 2006-10-11 | — | — | EP | disclosed |