Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198139 | 1.00 | TACR1 (0.37) | TACR1FAAHMGLLTRPM5TRPM4 | |
| Hydrochloric Acid SCHEMBL4126780 | 0.99 | TACR1 (0.36) | TACR1FAAHMGLLTRPM5TRPM4 | |
| Hydrochloric Acid SCHEMBL4126783 | 0.99 | TACR1 (0.36) | TACR1FAAHMGLLTRPM5TRPM4 | |
| SCHEMBL4119576 | 0.93 | SMN1; SMN2 (0.42) | FAAHMGLLPRKG1 | |
| SCHEMBL4119578 | 0.93 | SMN1; SMN2 (0.42) | FAAHMGLLPRKG1 | |
| SCHEMBL5227416 | 0.93 | TACR1 (0.42) | TACR1PRKG1TAAR1 | |
| SCHEMBL5227414 | 0.93 | TACR1 (0.42) | TACR1PRKG1TAAR1 | |
| SCHEMBL5198903 | 0.93 | TACR1 (0.42) | TACR1TAAR1 | |
| SCHEMBL4133742 | 0.93 | TACR1 (0.42) | TACR1TAAR1 | |
| SCHEMBL5198894 | 0.93 | TACR1 (0.42) | TACR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1710240-B1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | SERVIER LAB (FR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006106241-A1 | PIPERAZINE DERIVATIVES AND USE THEREOF AS SEROTONIN REUPTAKE INHIBITORS OR AS NEUROKININ ANTAGONISTS | LES LABORATOIRES SERVIER (FR) | 2006-10-12 | — | — | WO | disclosed |
| EP-1710240-A1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | Les Laboratoires Servier (FR) | 2006-10-11 | — | — | EP | disclosed |