Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5227448 | 0.83 | ALDH1A1 (0.44) | CHRM3HDAC2BCHEACHEMAOB | |
| SCHEMBL5228823 | 0.81 | F10 (0.53) | F10CHRM3HDAC2HDAC1BCHE | |
| SCHEMBL5260230 | 0.80 | F10 (0.52) | F10CHRM3HDAC2HDAC1BCHE | |
| SCHEMBL7406978 | 0.80 | HDAC3 (0.55) | CHRM3HDAC2HDAC1BCHEACHE | |
| Hydrochloric Acid SCHEMBL7245636 | 0.79 | HDAC2 (0.37) | F10HDAC2HDAC1HDAC3 | |
| SCHEMBL5258542 | 0.78 | CHRM3 (0.50) | F10CHRM3HDAC2HDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL5221482 | 0.78 | F10 (0.44) | F10CHRM3HDAC2HDAC1BCHE | |
| SCHEMBL5263815 | 0.77 | F10 (0.55) | F10 | |
| SCHEMBL5221853 | 0.76 | MAPK1 (0.46) | F10CHRM3BCHEACHEMAOB | |
| Hydrochloric Acid SCHEMBL5227078 | 0.76 | F10 (0.48) | F10CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |