Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388085 | 0.89 | F10 (0.58) | F10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5226288 | 0.88 | NPC1 (0.58) | F10NPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5223491 | 0.87 | NPC1 (0.85) | F10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4578928 | 0.85 | F10 (0.61) | F10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL20284424 | 0.84 | RAB9A (0.71) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL14527345 | 0.84 | SMN1; SMN2 (0.63) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL3821744 | 0.84 | F10 (0.93) | F10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1066986 | 0.83 | HDAC2 (0.76) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5188942 | 0.82 | NPC1 (1.00) | F10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14156007 | 0.80 | F10 (0.55) | F10NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |