Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 10/20 | 0.36 |
| ▸ | CALML3 | P27482 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896721 | 0.83 | CALML3 (0.41) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL5227937 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL5222880 | 0.82 | CALML3 (0.40) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL5223015 | 0.82 | CALML3 (0.42) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL2890506 | 0.82 | CALML3 (0.42) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL5223010 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL2896279 | 0.80 | MAOA (0.51) | MAOACALML3MAOB | |
| SCHEMBL2896788 | 0.80 | F10 (0.40) | KDM4EALDH1A1CYP2C19CYP3A4MAOA | |
| SCHEMBL3032598 | 0.79 | CALML3 (0.48) | CYP2C19CYP3A4MAOACALML3MAOB | |
| SCHEMBL2890769 | 0.79 | MAOA (0.44) | KDM4EALDH1A1MAOACALML3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799677-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | Ranbaxy Laboratories Limited (IN) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038100-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-13 | — | — | WO | disclosed |