Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570991 | 0.88 | POLB (0.66) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL5680365 | 0.86 | MEN1 (0.64) | KMT2AMEN1GAAALDH1A1SRC | |
| SCHEMBL2716922 | 0.83 | KLK7 (0.56) | KMT2AMEN1GAAALDH1A1SRC | |
| SCHEMBL28583980 | 0.83 | NPC1 (0.59) | KMT2AMEN1GAAALDH1A1CASR | |
| SCHEMBL14783002 | 0.81 | CA12 (0.70) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL3836963 | 0.80 | ROCK2 (0.58) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL6723553 | 0.80 | ROCK2 (0.58) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL11329740 | 0.80 | KMT2A (0.56) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL8508837 | 0.80 | FNTA (0.56) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL14842551 | 0.80 | POLB (0.70) | KMT2AMEN1GAAATMGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |