Quinaldic Acid

Quinaldic Acid

SCHEMBL5228655

O=C(O)c1ccc2ccccc2n1.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.96
CNR2 P34972 3/20 0.67
HDAC8 Q9BY41 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
RAB9A P51151 2/20 0.61
NFKB1 P19838 1/20 0.61
NFKB2 Q00653 1/20 0.61
RELA Q04206 1/20 0.61
ALDH1A1 P00352 4/20 0.59
MAPT P10636 2/20 0.59
GAA P10253 1/20 0.59
KDM4C Q9H3R0 1/20 0.57
KMT2A Q03164 4/20 0.57
HPGD P15428 3/20 0.57
MEN1 O00255 3/20 0.57
NPC1 O15118 1/20 0.57
TP53 P04637 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C9 P11712 1/20 0.57
KDM4E B2RXH2 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinaldic Acid SCHEMBL39024 0.98 MGAM (1.00) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL29350584 0.98 MGAM (1.00) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL1242670 0.98 MGAM (1.00) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL13571793 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL5228672 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL2372429 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL4587213 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL4588314 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL4802724 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A
Quinaldic Acid SCHEMBL8798794 0.96 MGAM (0.96) MGAMCNR2HDAC8SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116713121-A Flotation reagent combination for improving recovery of associated gold, silver, platinum and palladium minerals in chalcopyrite 商洛学院 2023-09-08 CN claimed
CN-116713121-A Flotation reagent combination for improving recovery of associated gold, silver, platinum and palladium minerals in chalcopyrite 商洛学院 2023-09-08 CN disclosed
CN-116713121-A Flotation reagent combination for improving recovery of associated gold, silver, platinum and palladium minerals in chalcopyrite 商洛学院 2023-09-08 CN disclosed
CN-104195533-B A kind of nickel zinc phosphorus chemical plating and preparation method thereof and chemical plating fluid 国家电网公司 2016-08-31 CN disclosed
CN-100482672-C novel 14 and 15 membered ring compounds GLAXO GROUP LTD (GB) 2009-04-29 CN disclosed
EP-1824871-A1 MACROLONE COMPOUNDS GLAXO GROUP LIMITED (GB) 2007-08-29 EP disclosed
EP-1628989-B1 NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS GLAXO GROUP LTD (GB) 2006-12-20 EP disclosed
CN-1852912-A Novel 14 and 15 membered-ring compounds GLAXO GROUP LTD (GB) 2006-10-25 CN disclosed
CN-1849328-A Novel 14 and 15 membered-ring compounds GLAXO GROUP LTD (GB) 2006-10-18 CN disclosed
EP-1628988-B1 NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS GLAXO GROUP LTD (GB) 2006-10-04 EP disclosed
CN-1820017-A Macrolides substituted at the 4 \"position GLAXO GROUP LTD (GB) 2006-08-16 CN disclosed
WO-2006050940-A1 MACROLONE COMPOUNDS GLAXO GROUP LIMITED (GB) 2006-05-18 WO disclosed
EP-1628989-A1 NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS GLAXO GROUP LIMITED (GB) 2006-03-01 EP disclosed
EP-1628988-A1 NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS GLAXO GROUP LIMITED (GB) 2006-03-01 EP disclosed
WO-2004101586-A1 NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS GLAXO GROUP LIMITED (GB) 2004-11-25 WO disclosed
WO-2004101587-A1 NOVEL 14 AND 15 MEMBERRED-RING COMPOUNDS GLAXO GROUP LIMITED (GB) 2004-11-25 WO disclosed
CN-1130346-C Tetrahydroquinolines as NMDA antagonists GLAXO WELLCOME SPA (IT) 2003-12-10 CN disclosed
EP-0854867-A1 TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS GLAXO WELLCOME S.p.A. (IT) 1998-07-29 EP disclosed
WO-1997012870-A1 TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS GLAXO WELLCOME S.P.A. (IT) 1997-04-10 WO disclosed