Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001541 | 0.90 | AVPR2 (0.61) | AVPR2AVPR1AOXTRLMNA | |
| SCHEMBL4195593 | 0.75 | AVPR2 (1.00) | AVPR2 | |
| SCHEMBL4868227 | 0.66 | POLB (0.60) | AVPR2AVPR1APRMT5WDR77POLB | |
| SCHEMBL4932308 | 0.66 | AVPR2 (0.78) | AVPR2 | |
| SCHEMBL4195589 | 0.66 | AVPR2 (1.00) | AVPR2 | |
| Dimethylamine SCHEMBL5264112 | 0.65 | AVPR2 (0.82) | AVPR2 | |
| SCHEMBL14089573 | 0.63 | MEN1 (0.62) | AVPR2AVPR1AOXTRPOLBLMNA | |
| SCHEMBL4863174 | 0.62 | SMN1; SMN2 (0.67) | AVPR2AVPR1AOXTRPOLBNPSR1 | |
| SCHEMBL4867294 | 0.62 | NOTUM (0.62) | AVPR2AVPR1AOXTRPOLBLMNA | |
| SCHEMBL10421954 | 0.61 | NPSR1 (0.71) | POLBLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294698-B1 | FUSED AZEPINE DERIVATIVES AND THEIR USE AS ANTIDIURETIC AGENTS | FERRING BV (NL) | 2007-08-01 | — | — | EP | disclosed |