Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228829 | 0.90 | AVPR2 (0.60) | AVPR2LMNAAVPR1AOXTR | |
| SCHEMBL4932308 | 0.76 | AVPR2 (0.78) | AVPR2 | |
| SCHEMBL4195589 | 0.76 | AVPR2 (1.00) | AVPR2 | |
| SCHEMBL4204579 | 0.73 | AVPR2 (0.70) | AVPR2 | |
| SCHEMBL4198269 | 0.72 | AVPR2 (0.85) | AVPR2OXTR | |
| SCHEMBL4206215 | 0.67 | AVPR2 (1.00) | AVPR2 | |
| SCHEMBL4195593 | 0.67 | AVPR2 (1.00) | AVPR2 | |
| SCHEMBL4868227 | 0.64 | POLB (0.60) | AVPR2LMNAAVPR1A | |
| SCHEMBL9530206 | 0.62 | NOTUM (0.62) | AVPR2MEN1ALDH1A1KMT2AAVPR1A | |
| SCHEMBL14089573 | 0.61 | MEN1 (0.62) | AVPR2MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154916-A1 | Condensed azepines as vasopressin agonists | FERRING BV | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154916-A1 | Condensed azepines as vasopressin agonists | AVPR2, AVPR1A, AVPR1B | AVPR2 1/4885MEN1 369/4885ALDH1A1 3007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.