Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228067 | 0.85 | FFAR1 (0.45) | FFAR1PPARAPPARGPOLBLTB4R | |
| SCHEMBL5224828 | 0.76 | FFAR1 (0.42) | FFAR1PPARAPPARGPOLB | |
| SCHEMBL5226575 | 0.75 | PPARA (0.46) | FFAR1PPARAPPARG | |
| SCHEMBL5224760 | 0.74 | PPARA (0.53) | FFAR1PPARAPPARG | |
| SCHEMBL5225160 | 0.68 | FFAR1 (0.48) | FFAR1PPARAPPARG | |
| SCHEMBL5231167 | 0.66 | PPARG (0.55) | FFAR1PPARAPPARGPOLB | |
| SCHEMBL5226738 | 0.64 | PPARA (0.49) | PPARAPPARG | |
| SCHEMBL5229270 | 0.63 | PPARA (0.51) | FFAR1PPARAPPARG | |
| SCHEMBL5261705 | 0.63 | PPARG (0.55) | PPARAPPARG | |
| SCHEMBL5231246 | 0.62 | FFAR1 (0.60) | FFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |