Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 14/20 | 0.40 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228067 | 0.87 | FFAR1 (0.45) | FFAR1PPARAPPARGLMNAPOLB | |
| SCHEMBL5228946 | 0.76 | FFAR1 (0.41) | FFAR1PPARAPPARGPOLB | |
| SCHEMBL5226575 | 0.72 | PPARA (0.46) | FFAR1PPARAPPARG | |
| SCHEMBL5224823 | 0.70 | PPARG (0.59) | PPARAPPARG | |
| SCHEMBL5224760 | 0.69 | PPARA (0.53) | FFAR1PPARAPPARG | |
| SCHEMBL5224964 | 0.68 | PPARG (0.59) | FFAR1PPARAPPARGMAPT | |
| SCHEMBL4873646 | 0.66 | CD274 (0.43) | PPARAPPARGPOLB | |
| SCHEMBL5223943 | 0.62 | PPARG (0.58) | FFAR1PPARAPPARGMAPT | |
| SCHEMBL5226750 | 0.62 | PPARG (0.58) | FFAR1PPARAPPARG | |
| SCHEMBL4810423 | 0.62 | CD274 (0.55) | FFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |