Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363013 | 0.94 | APEX1 (0.67) | KDM4EAPEX1ALDH1A1HPGDALOX15 | |
| SCHEMBL22336405 | 0.94 | APEX1 (0.67) | KDM4EAPEX1ALDH1A1HPGDALOX15 | |
| SCHEMBL261343 | 0.92 | KDM4E (0.64) | KDM4EAPEX1ALDH1A1ALOX15CDC25A | |
| SCHEMBL29404402 | 0.92 | KDM4E (0.64) | KDM4EAPEX1ALDH1A1ALOX15CDC25A | |
| SCHEMBL29439092 | 0.92 | KDM4E (0.64) | KDM4EAPEX1ALDH1A1ALOX15CDC25A | |
| SCHEMBL28680854 | 0.90 | KDM4E (0.62) | KDM4EAPEX1ALDH1A1ALOX15CDC25A | |
| SCHEMBL11798474 | 0.88 | KDM4E (0.61) | KDM4EAPEX1ALDH1A1ALOX15CDC25A | |
| SCHEMBL7536575 | 0.86 | APEX1 (0.79) | KDM4EAPEX1ALDH1A1HPGDALOX15 | |
| SCHEMBL3196569 | 0.85 | MCL1 (0.62) | KDM4EAPEX1ALDH1A1HPGDALOX15 | |
| SCHEMBL13627449 | 0.85 | SIRT1 (0.49) | KDM4EAPEX1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313407-B1 | Method for preparing polyimide and composite material thereof | MITSUI TOATSU CHEMICALS (JP) | 1996-05-08 | — | — | EP | claimed |
| CN-116854620-B | Abnormal phase separation inhibitor for PCBP1 gene encoding protein | 徐州医科大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-116854620-A | Abnormal phase separation inhibitor for PCBP1 gene encoding protein | 徐州医科大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-107239008-B | Image forming apparatus and process cartridge | 富士胶片商业创新有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-11229637-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-11229637-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-20210060000-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2021-03-04 | — | — | US | disclosed |
| US-20210060000-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2021-03-04 | — | — | US | disclosed |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| WO-2002005646-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | S.C. JOHNSON & SON, INC. (US) (US) | 2002-01-24 | — | — | WO | disclosed |
| EP-0474501-B1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0367482-B1 | Polyimides and process for the preparation thereof | MITSUI TOATSU CHEMICALS (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5322962-A | Produce polyimides with high heat and chemical resistance, processability | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-06-21 | — | — | US | disclosed |
| US-5231160-A | AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0474501-A1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |
| EP-0367482-A1 | Polyimides and process for the preparation thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-09 | — | — | EP | disclosed |
| EP-0303598-A1 | POLYETHERIMIDE-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
| WO-1988006170-A1 | POLYETHERIMIDE-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1988-08-25 | — | — | WO | disclosed |
| US-4490266-A | Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229637-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | HIF1AN, HIF1A, EGLN2 | KDM4E 1774/4885APEX1 1019/4885ALDH1A1 1476/4885 |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | HIF1AN, HIF1A, EGLN2 | KDM4E 1774/4885APEX1 1019/4885ALDH1A1 1476/4885 |
| US-20210060000-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | HIF1AN, EGLN2, HIF1A | KDM4E 1814/4885APEX1 716/4885ALDH1A1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.