Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.54 |
| ▸ | CTSD | P07339 | 15/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713938 | 0.83 | CTSD (0.67) | BACE1CTSD | |
| SCHEMBL3177017 | 0.83 | CTSD (0.67) | BACE1CTSD | |
| SCHEMBL3167952 | 0.83 | CTSD (0.67) | BACE1CTSD | |
| SCHEMBL4262818 | 0.80 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| SCHEMBL3172063 | 0.76 | BACE1 (0.80) | BACE1CTSD | |
| SCHEMBL3172074 | 0.76 | BACE1 (0.80) | BACE1CTSD | |
| SCHEMBL3502935 | 0.76 | BACE1 (0.80) | BACE1CTSD | |
| SCHEMBL13315982 | 0.76 | BACE1 (0.68) | BACE1CTSD | |
| Hydrochloric Acid SCHEMBL3172335 | 0.75 | BACE1 (0.67) | BACE1CTSD | |
| Hydrochloric Acid SCHEMBL3172343 | 0.75 | BACE1 (0.67) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565443-A4 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARM INC (US) | 2007-07-18 | — | — | EP | claimed |
| JP-2006504793-A | — | — | 2006-02-09 | — | — | JP | claimed |
| EP-1565443-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | Elan Pharmaceuticals, Inc. (US) | 2005-08-24 | — | — | EP | claimed |
| WO-2004024081-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-25 | — | — | WO | claimed |