Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL381675 | 0.87 | TSHR (0.44) | SLC22A1SLC22A2ALDH1A1TSHRSMN1; SMN2 | |
| Tetrabuthylammonium SCHEMBL29202179 | 0.81 | SLC22A1 (0.71) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL492357 | 0.78 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL22384 | 0.78 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL71525 | 0.78 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL2007037 | 0.78 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28192774 | 0.75 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL25266692 | 0.74 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL10866345 | 0.74 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL2580744 | 0.74 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1826231-A2 | Organohydridosiloxane Resins With High Organic Content | AlliedSignal Inc. (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-0977797-B1 | ORGANOHYDRIDOSILOXANE RESINS WITH HIGH ORGANIC CONTENT | ALLIED SIGNAL INC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2004046224-A1 | ORGANOHYDRIDOSILOXANE RESINS WITH HIGH ORGANIC CONTENT | HONEYWELL INTERNATIONAL INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20030176614-A1 | Organohydridosiloxane resins with high organic content | HONEYWELL INTERNATIONAL INC. | 2003-09-18 | — | — | US | disclosed |
| US-6512071-B1 | An organohydridosiloxane polymer having a cage conformation, at least approximately 40 Mole percent carbon containing substituents and a dielectric constant of less than about 2.7 is presented. Each silicon atom of the cage polymer is bonded | HONEYWELL INTERNATIONAL INC. | 2003-01-28 | — | — | US | disclosed |
| US-6143855-A | EACH SILICON ATOM IS BONDED TO AT LEAST THREE OXYGEN ATOMS AND TO EITHER A HYROGEN ATOM OR ORGANIC SUBSTITUENT; NO HYDROXYL OR ALKOXY SUBSTITUENTS; USE AS LOW DIELECTRIC FILM | ALLIEDSIGNAL INC. (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0977797-A1 | ORGANOHYDRIDOSILOXANE RESINS WITH HIGH ORGANIC CONTENT | AlliedSignal Inc. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047944-A1 | ORGANOHYDRIDOSILOXANE RESINS WITH HIGH ORGANIC CONTENT | ALLIEDSIGNAL INC. (US) | 1998-10-29 | — | — | WO | disclosed |