Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | KAT7 | O95251 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383877 | 0.96 | HTR6 (0.50) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL22623274 | 0.94 | ACKR3 (0.53) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL22617003 | 0.94 | ACKR3 (0.53) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL29605986 | 0.94 | ACKR3 (0.53) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL3358109 | 0.91 | HTR6 (0.51) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL3361572 | 0.91 | HTR6 (0.51) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL3356609 | 0.91 | HTR6 (0.51) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL22616960 | 0.89 | ACKR3 (0.52) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL34468715 | 0.86 | JAK2 (0.50) | HTR6BCHEACKR3USP30JAK2 | |
| SCHEMBL5237806 | 0.85 | SMN1; SMN2 (0.51) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |