Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.71 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.71 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229489 | 0.93 | DPP4 (0.72) | DPP4DPP7DPP9DPP8CYP2D6 | |
| SCHEMBL5227592 | 0.86 | DPP4 (0.70) | DPP4DPP7DPP9DPP8CYP2D6 | |
| SCHEMBL5225939 | 0.83 | DPP4 (1.00) | DPP4DPP7DPP9DPP8CYP2D6 | |
| Hydrochloric Acid SCHEMBL5237003 | 0.82 | DPP4 (0.98) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL5229043 | 0.76 | DPP4 (1.00) | DPP4DPP7DPP9DPP8CYP2D6 | |
| SCHEMBL5228869 | 0.76 | DPP4 (0.54) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL28711236 | 0.72 | DPP4 (0.51) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL28710941 | 0.72 | DPP4 (0.51) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL3608475 | 0.71 | DPP4 (0.48) | DPP4DPP9DPP8 | |
| SCHEMBL13501540 | 0.71 | DPP4 (0.48) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554280-B1 | ANTIDIABETIC BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS | MERCK & CO INC (US) | 2007-08-15 | — | — | EP | disclosed |