⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224204 | 0.94 | — | — | |
| SCHEMBL28527 | 0.87 | CA1 (0.32) | — | |
| SCHEMBL23227942 | 0.84 | CA1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9085192 | 0.84 | CA1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL28207127 | 0.84 | CA1 (0.30) | — | |
| Bromide SCHEMBL4662499 | 0.84 | CA1 (0.30) | — | |
| SCHEMBL5565770 | 0.84 | CA1 (0.30) | — | |
| Methylene Chloride SCHEMBL5612394 | 0.78 | — | — | |
| Acetonitrile SCHEMBL9682998 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL28213438 | 0.77 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632490-B1 | STEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC (CA) | 2007-08-22 | — | — | EP | disclosed |
| US-7230100-B2 | Stereoselective method for the preparation of nucleosides | SHIRE BIOCHEM., INC. (CA) | 2007-06-12 | — | — | US | disclosed |
| EP-1406896-B8 | STEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC (CA) | 2006-11-15 | — | — | EP | disclosed |
| US-7109334-B2 | Stereoselective methods for the preparation of nucleosides | SHIRE BIOCHEM, INC. (CA) | 2006-09-19 | — | — | US | disclosed |
| US-20060183899-A1 | Stereoselective method for the preparation of nucleosides | YU QING | 2006-08-17 | — | — | US | disclosed |
| EP-1632490-A1 | STEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | Shire Biochem Inc. (CA) | 2006-03-08 | — | — | EP | disclosed |
| EP-1406896-B1 | ATEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC (CA) | 2005-12-21 | — | — | EP | disclosed |
| EP-1406896-A1 | ATEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | Shire Biochem Inc. (CA) | 2004-04-14 | — | — | EP | disclosed |
| US-20030135048-A1 | Stereoselective methods for the preparation of nucleosides | SHIRE BIOCHEM INC. (CA) | 2003-07-17 | — | — | US | disclosed |
| WO-2002102796-A1 | STEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2002-12-27 | — | — | WO | disclosed |