Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427500 | 0.96 | CCR3 (0.44) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL1588025 | 0.91 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL7868181 | 0.88 | CCR3 (0.51) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL13596992 | 0.85 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL8984029 | 0.84 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL325460 | 0.84 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL10755262 | 0.84 | CCR3 (0.44) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL5242533 | 0.80 | SLC6A4 (0.53) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL6263887 | 0.80 | SIGMAR1 (0.52) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL23063982 | 0.78 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR1AHTR2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006316-B2 | 9H-pyrrolo-dipyridine derivatives | UCB Biopharma SRL (BE) | 2024-06-11 | — | — | US | disclosed |
| US-20220213103-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-07-07 | — | — | US | disclosed |
| US-20220213103-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-07-07 | — | — | US | disclosed |
| US-11312716-B2 | 9H-pyrrolo-dipyridine derivatives | UCB Biopharma SRL | 2022-04-26 | — | — | US | disclosed |
| US-11312716-B2 | 9H-pyrrolo-dipyridine derivatives | UCB Biopharma SRL | 2022-04-26 | — | — | US | disclosed |
| EP-3253762-B1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-05-05 | — | — | EP | disclosed |
| EP-3253762-B1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-05-05 | — | — | EP | disclosed |
| US-20210047326-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2021-02-18 | — | — | US | disclosed |
| US-20210047326-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2021-02-18 | — | — | US | disclosed |
| CN-107207508-B | 9H-pyrrolo-bipyridine derivatives | UCB生物制药私人有限公司 | 2020-02-28 | — | — | CN | disclosed |
| WO-2016124508-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016124508-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-11 | — | — | WO | disclosed |
| EP-1818326-A1 | Nitrogen-containing heterocyclic compounds and pharmaceutical composition containing the compounds | Eisai R&D Management Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |
| EP-1818326-A1 | Nitrogen-containing heterocyclic compounds and pharmaceutical composition containing the compounds | Eisai R&D Management Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |
| EP-1254895-B1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | EISAI R&D MAN CO LTD (JP) | 2007-05-23 | — | — | EP | disclosed |
| EP-1254895-B1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | EISAI R&D MAN CO LTD (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-20060084658-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-04-20 | — | — | US | disclosed |
| US-6906072-B1 | Piperazine compound and pharmaceutical composition containing the compound | EISAI CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20040220193-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | EISAI CO., LTD. | 2004-11-04 | — | — | US | disclosed |
| EP-1254895-A1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213103-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | MAPT, PSEN1, PRNP | SIGMAR1 2081/4885DRD2 200/4885HTR1A 884/4885 |
| US-20210047326-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | MAPT, PSEN1, PRNP | SIGMAR1 2081/4885DRD2 200/4885HTR1A 884/4885 |
| US-12006316-B2 | 9H-pyrrolo-dipyridine derivatives | MAPT, PSEN1, PRNP | SIGMAR1 2081/4885DRD2 200/4885HTR1A 884/4885 |
| US-20040220193-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | CACNA1D, CACNA1B, CACNA1E | SIGMAR1 143/4885DRD2 43/4885HTR1A 126/4885 |
| US-11312716-B2 | 9H-pyrrolo-dipyridine derivatives | MAPT, PSEN1, PRNP | SIGMAR1 2081/4885DRD2 200/4885HTR1A 884/4885 |
| US-20060084658-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | CACNA1B, CACNA1E, CACNA1D | SIGMAR1 133/4885DRD2 97/4885HTR1A 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.