Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237010 | 0.95 | EGFR (0.39) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5234807 | 0.92 | EGFR (0.37) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2990712 | 0.90 | EGFR (0.41) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5228235 | 0.88 | EGFR (0.39) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5231614 | 0.86 | EGFR (0.38) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5232127 | 0.86 | EGFR (0.38) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5233254 | 0.85 | TACR1 (0.36) | TACR1LMNAKMT2ATP53 | |
| SCHEMBL5228571 | 0.84 | EGFR (0.39) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2995605 | 0.84 | EGFR (0.43) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5234485 | 0.83 | EGFR (0.36) | EGFRTYMSLTA4HVDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |