Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231069 | 0.95 | LSS (0.36) | TACR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5227454 | 0.91 | ALDH1A1 (0.34) | TACR1LMNAADORA1KDM4EMEN1 | |
| SCHEMBL2998567 | 0.88 | TACR1 (0.37) | TACR1LMNATP53BCL2L1ADORA1 | |
| SCHEMBL5229977 | 0.85 | CNR1 (0.36) | TACR1TP53ALDH1A1CNR1LSS | |
| SCHEMBL5230751 | 0.85 | EGFR (0.38) | TACR1LMNATP53KMT2A | |
| SCHEMBL3001005 | 0.82 | MEN1 (0.36) | TACR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5234741 | 0.79 | CNR1 (0.34) | TP53KDM4EALDH1A1CNR1CYP3A4 | |
| SCHEMBL2997420 | 0.79 | MEN1 (0.36) | TACR1LMNAADORA1KDM4EMEN1 | |
| SCHEMBL5237010 | 0.79 | EGFR (0.39) | TACR1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL2996688 | 0.78 | MMP2 (0.35) | TACR1BCL2L1CNR1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |