SCHEMBL5230858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5236345	0.87	ZAP70 (0.56)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL5235053	0.83	ZAP70 (0.56)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL3243299	0.80	SMN1; SMN2 (0.49)	ACVR1ZAP70ERN1
	SCHEMBL5623507	0.79	ZAP70 (0.54)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL5234898	0.78	ZAP70 (0.53)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL13136625	0.77	ZAP70 (0.52)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL5232609	0.76	ZAP70 (0.55)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL3243297	0.76	ZAP70 (0.47)	ACVR1ZAP70ERN1PRKD3PRKCG
	SCHEMBL5232807	0.76	ERN1 (0.52)	ZAP70ERN1PRKD3PRKCGPRKCB
	SCHEMBL13136628	0.74	ZAP70 (0.50)	ACVR1ZAP70ERN1PRKD3PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.