Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 20/20 | 1.00 |
| ▸ | GABRB3 | P28472 | 20/20 | 1.00 |
| ▸ | GABRA3 | P34903 | 20/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228691 | 0.92 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5228577 | 0.91 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5229593 | 0.90 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5231195 | 0.89 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5229856 | 0.88 | GABRG2 (0.87) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5229380 | 0.88 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5232089 | 0.88 | GABRG2 (0.89) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5228746 | 0.88 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5229372 | 0.88 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL5231914 | 0.87 | GABRG2 (1.00) | GABRG2GABRB3GABRA3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121361-B1 | PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2007-08-29 | — | — | EP | claimed |
| US-6476030-B1 | Pyrazolo-triazine derivatives as ligands for GABA receptors | MERCK SHARP & DOHME LTD. | 2002-11-05 | — | — | US | claimed |
| EP-1121361-B1 | PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2007-08-29 | — | — | EP | disclosed |
| EP-0620268-B2 | Use of overbased additives to improve the gear change properties of oils for synchromesh gears | AFTON CHEMICAL LTD (GB) | 2007-08-22 | — | — | EP | disclosed |
| US-20070054813-A1 | BORON FREE AUTOMOTIVE GEAR OIL | AFTON CHEMICAL CORPORATION | 2007-03-08 | — | — | US | disclosed |
| US-20050070446-A1 | Boron free automotive gear oil | ETHYL PETROLEUM ADDITIVES, INC. | 2005-03-31 | — | — | US | disclosed |
| EP-1518919-A1 | Boron free automotive gear oil | Afton Chemical Corporation (US) | 2005-03-30 | — | — | EP | disclosed |
| US-6476030-B1 | Pyrazolo-triazine derivatives as ligands for GABA receptors | MERCK SHARP & DOHME LTD. | 2002-11-05 | — | — | US | disclosed |
| EP-0747465-B1 | Use of transmission and gear oil lubricants having enhanced friction properties | ETHYL PETROLEUM ADDITIVES LTD (GB) | 2001-02-28 | — | — | EP | disclosed |
| US-6096691-A | Gear oil additive concentrates and lubricants containing them | ETHYL CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0620268-B1 | Use of overbased additives to improve the gear change properties of oils for synchromesh gears | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5571445-A | Gear oil compositions | ETHYL CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| US-5492638-A | OVERBASED COMPOUND | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1996-02-20 | — | — | US | disclosed |
| US-5464549-A | Oil soluble dispersants suitable for use in fuels and lubricants | ETHYL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| US-5358650-A | Gear oil compositions | ETHYL CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |
| EP-0620268-A1 | Gear oil lubricants of enhanced friction properties | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1994-10-19 | — | — | EP | disclosed |
| US-5241003-A | Post-treated polyisobutenyl succinimide; crankcase, transmission oils | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0531585-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |
| US-5137980-A | Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-08-11 | — | — | US | disclosed |