Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569172 | 0.76 | TACR3 (0.39) | TACR3 | |
| SCHEMBL5225184 | 0.74 | DPP4 (0.39) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL5225207 | 0.74 | DPP4 (0.38) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL5230441 | 0.73 | DPP4 (0.39) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL5231125 | 0.73 | DPP4 (0.41) | DPP4DPP7 | |
| SCHEMBL13677264 | 0.72 | DPP4 (0.42) | DPP4DPP7LRRK2 | |
| SCHEMBL13676978 | 0.69 | DPP4 (0.43) | DPP4DPP7LRRK2 | |
| SCHEMBL5654734 | 0.68 | TACR3 (0.39) | DPP4TACR3 | |
| SCHEMBL14970399 | 0.67 | DPP4 (0.56) | DPP4DPP7TACR3LRRK2 | |
| SCHEMBL31409374 | 0.67 | PLAT (0.34) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554280-B1 | ANTIDIABETIC BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS | MERCK & CO INC (US) | 2007-08-15 | — | — | EP | disclosed |