SCHEMBL31409374

SCHEMBL31409374

CC1NCCn2nc(C(F)(F)F)cc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLAT P00750 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CRACR2A Q9BSW2 2/20 0.30
TACR3 P29371 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25431955 0.76
SCHEMBL24942446 0.76 SLC6A2 (0.30)
SCHEMBL25430904 0.76
SCHEMBL31389754 0.72
SCHEMBL31389630 0.71 RIPK1 (0.39) PLATALDH1A1
SCHEMBL24276771 0.70 CDC7 (0.30)
SCHEMBL14926120 0.70
SCHEMBL5231302 0.67 DPP4 (0.35) TACR3
SCHEMBL5654734 0.67 TACR3 (0.39) TACR3
SCHEMBL31692182 0.67 SLC6A2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038920-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS, INC. (CA) 2025-02-20 WO disclosed
WO-2025038917-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS INC. (CA) 2025-02-20 WO disclosed