SCHEMBL523164

SCHEMBL523164

CCCCCC[Si](C)(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.43
DNM1 Q05193 8/20 0.38
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032434 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL236877 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL20359860 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8861935 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9642368 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9643016 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL523911 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL5843537 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL367260 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6037417 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899387-A Method for preparing polycarbosilane by using Grignard reagent 汕头大学 2025-04-29 CN claimed
WO-2024155487-A1 COMPOSITE SILICA SORBENTS PPG INDUSTRIES OHIO, INC. (US) 2024-07-25 WO claimed
CN-117903695-A Solid super-smooth surface and construction method and application thereof 青岛理工大学 2024-04-19 CN claimed
CN-117186536-A Environment-friendly sole material with light weight function and preparation method thereof 东莞市迪强贸易有限公司 2023-12-08 CN claimed
CN-114804648-B Fluorine-free self-cleaning coating and preparation method and application thereof 中国科学院福建物质结构研究所 2023-10-03 CN claimed
CN-114805820-B Hydrophobic organic polysilazane and preparation method and application thereof 中国船舶重工集团公司第七一八研究所 2023-05-02 CN claimed
CN-114804648-A Fluorine-free self-cleaning coating and preparation method and application thereof 中国科学院福建物质结构研究所 2022-07-29 CN claimed
EP-2751209-B1 METHODS OF PRODUCING A TITANIUM DIOXIDE PIGMENT AND IMPROVING THE PROCESSABILITY OF TITANIUM DIOXIDE PIGMENT PARTICLES TRONOX LLC (US) 2020-09-30 EP claimed
EP-1735823-B1 THE SURFACE OF TREATMENT OF NANOPARTICLES TO CONTROL INTERFACIAL PROPERTIES AND METHOD OF MANUFACTURE NANOPHASE TECH CORP (US) 2017-02-22 EP claimed
CN-103814090-B The method preparing TiO 2 pigment and the method for the machinability improving titanium dioxide pigment particles 特罗诺克斯有限公司 2016-10-05 CN claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
US-6033781-A Ceramic powders coated with siloxane star-graft polymers NANOPHASE TECHNOLOGIES CORPORATION (US) 2000-03-07 US claimed
US-5993967-A Siloxane star-graft polymers, ceramic powders coated therewith and method of preparing coated ceramic powders NANOPHASE TECHNOLOGIES CORPORATION (US) 1999-11-30 US claimed
EP-0891387-A2 SILOXANE STAR-GRAFT POLYMERS, CERAMIC POWDERS COATED THEREWITH AND METHOD OF PREPARING COATED CERAMIC POWDERS NANOPHASE TECHNOLOGIES CORPORATION (US) 1999-01-20 EP claimed
WO-1997038041-A1 SILOXANE STAR-GRAFT POLYMERS, CERAMIC POWDERS COATED THEREWITH AND METHOD OF PREPARING COATED CERAMIC POWDERS NANOPHASE TECHNOLOGIES CORPORATION (US) 1997-10-16 WO claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-5286891-A Hydrolysis of chloro-termianted polysilane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-02-15 US claimed
US-4997899-A Organosilicon or germanium polymers NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-05 US claimed
US-4925963-A Process for reduction of organosilicon halides ETHYL CORPORATION (US) 1990-05-15 US claimed