Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032434 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL236877 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL20359860 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL8861935 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9642368 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9643016 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5843537 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL523164 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL367260 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6037417 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262515-B | A kind of granular random/stereoblock polystyrene preparation method | 沈阳化工大学 | 2017-08-08 | — | — | CN | claimed |
| CN-105399910-A | A styrene-conjugated diene block copolymer and a preparing method thereof | UNIV SHENYANG CHEMICAL TECH | 2016-03-16 | — | — | CN | claimed |
| CN-104262515-A | Method for preparing granular random/stereoblock polystyrene | UNIV SHENYANG CHEMICAL TECH | 2015-01-07 | — | — | CN | claimed |
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | claimed |
| EP-1546267-B1 | HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF | DOW CORNING (US) | 2006-05-31 | — | — | EP | claimed |
| EP-1546267-A2 | HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF | Dow Corning Corporation (US) | 2005-06-29 | — | — | EP | claimed |
| US-20040227127-A1 | Hydrophobing silica with organosilicon compounds and blends thereof | BOSWELL LISA MARIE (US) | 2004-11-18 | — | — | US | claimed |
| US-6811823-B2 | CONTACTING SILICA SURFACES WITH DIALKYLDICHLOROSILANES AND TRIALKOXYSILANES THAT ARE FREE OF REACTIVE HYDROCARBON OF ORGANOFUNCTIONAL GROUPS; RUBBER TIRES | DOW CORNING CORPORATION | 2004-11-02 | — | — | US | claimed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2004024831-A2 | HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF | DOW CORNING CORPORATION (US) | 2004-03-25 | — | — | WO | claimed |
| US-20040052939-A1 | Hydrophobing silica with organosilicon compounds and blends thereof | DOW CORNING CORPORATION | 2004-03-18 | — | — | US | claimed |
| US-6703497-B1 | SURFACE MODIFIED BY HAVING HYDROXYL FUNCTIONAL GROUPS PRESENT AT THE SURFACE ETHERIFIED BY ORGANIC COMPOUND COMPRISING SILYLATING AGENT, ISOCYANATE, HALOGENATED ALKYLATING AGENT, ALKYLENE OXIDE, OR GLYCIDYL COMPOUND | RHODIA CHIMIE (FR) | 2004-03-09 | — | — | US | claimed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | claimed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | claimed |
| EP-0799851-A2 | Preparation of polyorganosilloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | claimed |
| US-20250091263-A1 | Low-Pore Pellets and Methods for Producing Molded Body | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-03-20 | — | — | US | disclosed |
| CN-119608184-A | Ball-milling catalytic hydrosilylation reaction method and catalyst used in same | 浙江大学 | 2025-03-14 | — | — | CN | disclosed |
| WO-1990002107-A1 | A METHOD OF COATING SILICON CARBIDE FIBERS | ALLIED-SIGNAL INC. (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4490216-A | MULTILAYER ELECTROCONDUCTIVE LAYER, HYDROPHILIC AND HYDROPHOBIC LIPID LAYER | MOLECULAR DEVICES CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-3962299-A | Organopolysiloxane polyesters | CELANESE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | NOS2, NOS1, NOS3 | TSHR 2005/4885THRB 3599/4885ALDH1A1 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.