SCHEMBL5232123

SCHEMBL5232123

CC(N)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3713171 1.00
SCHEMBL19900855 1.00
Hydrochloric Acid SCHEMBL7962851 0.96
Hydrochloric Acid SCHEMBL29429357 0.96
Hydrochloric Acid SCHEMBL16213498 0.96
SCHEMBL18067015 0.78
SCHEMBL19573885 0.75
Hydrochloric Acid SCHEMBL20969304 0.75
SCHEMBL18011037 0.73
SCHEMBL1269508 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016183101-A1 PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-17 WO claimed
EP-1392693-B1 TRIAZOLOPYRIMIDINES FUNGICIDES BAYER CROPSCIENCE AG (DE) 2007-02-07 EP claimed
US-20040176398-A1 Triazolopyrimidines BAYER CROPSCIENCE AG (DE) 2004-09-09 US claimed
US-20040157863-A1 Triazolopyrimidines BAYER CROPSCIENCE AG (DE) 2004-08-12 US claimed
US-20040142943-A1 Triazolopyrimidines BAYER CROPSCIENCE AG (DE) 2004-07-22 US claimed
EP-1397362-A2 TRIAZOLOPYRIMIDINES HAVING A FUNGICIDAL EFFECT Bayer CropScience AG (DE) 2004-03-17 EP claimed
EP-1392693-A1 TRIAZOLOPYRIMIDINES Bayer CropScience AG (DE) 2004-03-03 EP claimed
EP-1392695-A2 TRIAZOLOPYRIMIDINES Bayer CropScience AG (DE) 2004-03-03 EP claimed
WO-2002088126-A1 TRIAZOLOPYRIMIDINES BAYER CROPSCIENCE AG (DE) 2002-11-07 WO claimed
WO-2002088127-A2 TRIAZOLOPYRIMIDINES BAYER CROPSCIENCE AG (DE) 2002-11-07 WO claimed
WO-2002088125-A2 TRIAZOLOPYRIMIDINES HAVING A FUNGICIDAL EFFECT BAYER CROPSCIENCE AG (DE) 2002-11-07 WO claimed
US-6265616-B1 Manufacture of trifluorisopropylamine HONEYWELL INTERNATIONAL INC. 2001-07-24 US claimed
CN-118684662-A Pyrrolopyridone-containing compounds 正大天晴药业集团股份有限公司 2024-09-24 CN disclosed
CN-115572269-B N-trifluoro isopropyl azole and indole compound and preparation method thereof 广州大学 2024-05-17 CN disclosed
CN-109251158-B Thioamidine amide compounds and use thereof for treating hepatitis B 上海长森药业有限公司 2023-05-23 CN disclosed
US-11591334-B2 Substituted pyrrolizines for the treatment of hepatitis B SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) 2023-02-28 US disclosed
US-6265616-B1 Manufacture of trifluorisopropylamine HONEYWELL INTERNATIONAL INC. 2001-07-24 US disclosed
US-6265616-B1 Manufacture of trifluorisopropylamine HONEYWELL INTERNATIONAL INC. 2001-07-24 US disclosed
US-6204269-B1 Fungicidal trifluoromethylalkylamino-triazolopyrimidines AMERICAN CYANAMID CO. 2001-03-20 US disclosed
US-5986135-A CHEMICAL INTERMEDIATES AMERICAN CYANAMID COMPANY (US) 1999-11-16 US disclosed